DAT1 Polymorphism Determines L-DOPA Effects on Learning about Others’ Prosociality
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چکیده
منابع مشابه
DAT1 Polymorphism Determines L-DOPA Effects on Learning about Others’ Prosociality
Despite that a wealth of evidence links striatal dopamine to individualś reward learning performance in non-social environments, the neurochemical underpinnings of such learning during social interaction are unknown. Here, we show that the administration of 300 mg of the dopamine precursor L-DOPA to 200 healthy male subjects influences learning about a partners' prosocial preferences in a novel...
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Rats received intracisternal 1aIlnorepinephrine and, after 5 min, intraperitoneal L-dopa (100 mg/kg); they were killed at intervals during the subsequent 24 hr. Their brains were assayed for norepinephrile, L-dopa, S-adenosylmethionine, and [aH]norepilnephrine and its metabolites. Rats that received L-dopa had markedly lower brain concentrations of S-adenosylnethionine and of O-methylated metab...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0067820